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Dr. Paul discusses depression in this first of a two-part series on the D word. Dr. Paul explains what depression means by defining the disorder by describing the several different symptoms and the diagnostic criteria to make the diagnosis. He explains that depression is a pervasive set of symptoms that is beyond just having a bad day here and there. Dr. Paul explains that people who are depressed are just not feeling their old selves, and this can be a hopeless condition that can even be life-threatening. He addresses the stigma that holds people back from getting the treatment that they need. He instills hope that this is an easily treated condition, since it is a medical problem with groundbreaking medical solutions.